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High Purity Ingenol-3-angelate (CAS 75567-37-2) | ≥98% Research Grade PKC Activator
Ingenol-3-angelate (CAS 75567-37-2), also known as PEP005 or Ingenol mebutate, is a diterpene ester derived from Euphorbia peplus. It is a potent Protein Kinase C (PKC) activator widely studied for its anticancer, pro-apoptotic, and immunomodulatory activities. We supply ≥98% high-purity research grade Ingenol-3-angelate with COA, HPLC, MSDS, and worldwide shipping support, suitable for pharmaceutical, biomedical, and natural product research.
Product Name :
Ingenol-3-angelateCAS No. :
75567-37-2Appearance :
Fine White PowderSpecification :
98%Product Name: Ingenol-3-angelate
Synonyms: Ingenol mebutate; PEP005; Euphorbia diterpene ester
CAS Number: 75567-37-2
Molecular Formula: C25H34O6
Molecular Weight: 430.53 g/mol
Appearance: White to off-white powder
Source: Derived from Euphorbia peplus (Spurge)
Category: Natural diterpene ester / Bioactive compound
?? What is Ingenol-3-angelate?
Ingenol-3-angelate (CAS: 75567-37-2), also known as PEP005 or Ingenol mebutate, is a semi-synthetic diterpene ester originally isolated from the plant Euphorbia peplus.
It is a potent Protein Kinase C (PKC) activator, widely studied for its anticancer, pro-apoptotic, immunomodulatory, and antiviral activities.
As a bioactive natural product, Ingenol-3-angelate has been applied in cancer biology, immunology, and drug discovery research. It has also been investigated in clinical studies for the treatment of actinic keratosis and other dermatological conditions.
We provide high-purity Ingenol-3-angelate (≥98%) for scientific research and industrial applications.
?? Ingenol-3-angelate 98% (Research Grade)
?? High Purity: ≥98% verified by HPLC
?? Research Grade: Suitable for pharmaceutical, biomedical, and natural product studies
?? Multiple Bioactivities: PKC activation, anticancer, pro-apoptotic, and immunomodulatory effects
?? Technical Support: COA, HPLC chromatograms, MS, and NMR data available
Pharmaceutical Research: Studied for its role in skin disease treatments and cancer therapy.
Biomedical Studies: Applied in apoptosis, necrosis, immune response, and signal transduction research.
Immunology & Virology: Explored as an HIV latency-reversing agent and immune activator.
Natural Product Development: A diterpene ester derivative with potential in topical drug delivery systems.
?? Technical Specifications (98% Grade)
Item | Specification |
---|---|
Product Name | Ingenol-3-angelate |
CAS Number | 75567-37-2 |
Molecular Formula | C25H34O6 |
Molecular Weight | 430.53 g/mol |
Appearance | White to off-white powder |
Purity | ≥98% (HPLC) |
Source | Euphorbia peplus |
Solubility | Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate; poorly soluble in water |
Storage | Store at –20 °C, dry and protected from light |
Shelf Life | 24 months under proper storage conditions |
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